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A manuscript (abbreviated MS for singular and MSS for plural) was, traditionally, any document written by hand or typewritten, as opposed to mechanically printed or reproduced in some indirect or automated way. More recently, the term has come to be understood to further include any written, typed, or word-processed copy of an author's work, as distinguished from the rendition as a printed version of the same.
Before the arrival of prints, all documents and books were manuscripts. Manuscripts are not defined by their contents, which may combine writing with mathematical calculations, maps, music notation, explanatory figures, or illustrations.